{"id":5293,"date":"2006-06-06T21:54:00","date_gmt":"2006-06-06T21:54:00","guid":{"rendered":"https:\/\/inveske.co.uk\/esteroides-e-saude-mental-uma-agenda-abortada\/"},"modified":"2006-06-06T21:54:00","modified_gmt":"2006-06-06T21:54:00","slug":"esteroides-e-saude-mental-uma-agenda-abortada","status":"publish","type":"post","link":"https:\/\/www.mariliacoutinho.com\/pt-br\/esteroides-e-saude-mental-uma-agenda-abortada\/","title":{"rendered":"Ester\u00f3ides e sa\u00fade mental \u2013 uma agenda abortada"},"content":{"rendered":"
Fiz um levantamento na literatura m\u00e9dica por pesquisas relativas ao efeito e emprego de ester\u00f3ides androg\u00eanicos anab\u00f3licos em sa\u00fade mental. Quanto \u00e0s d\u00e9cadas recentes, observei o \u00f3bvio: nenhuma pesquisa. Tudo que h\u00e1 em rela\u00e7\u00e3o ao tema s\u00e3o relatos de uma suposta depend\u00eancia de ester\u00f3ides e seus desdobramentos negativos. No entanto, expandindo a busca para datas mais antigas, descobri algo surpreendente. Entre 1951 e 1962 houve pesquisa envolvendo o emprego de ester\u00f3ides em pacientes de desordens mentais. Como os artigos s\u00e3o muito antigos, n\u00e3o pude ainda ler seu conte\u00fado. Os t\u00edtulos, no entando, indicam uma agenda de pesquisa possivelmente f\u00e9rtil \u2013 nenhum t\u00edtulo com evid\u00eancias de aus\u00eancia de efeito ou efeito negativo. S\u00e3o 20 artigos sendo 11 deles publicados em outras l\u00ednguas que n\u00e3o o ingl\u00eas (a maior parte destes artigos \u201cestrangeiros\u201d s\u00e3o italianos).<\/div>\n
 <\/div>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
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Ano<\/span><\/div>\n<\/td>\n
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Peri\u00f3dico<\/span><\/div>\n<\/td>\n
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T\u00edtulo<\/span><\/div>\n<\/td>\n
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Autores<\/span><\/div>\n<\/td>\n<\/tr>\n
\n
1951<\/span><\/div>\n<\/td>\n
\n
Rev Med Cienc Afines. 1951 May;9(106):654-85. <\/span><\/div>\n<\/td>\n
\n
[Action of testosterone propionate on the psychical state in aged.]<\/span><\/div>\n<\/td>\n
\n
PASCUAL DEL RONCAL F.<\/span><\/div>\n<\/td>\n<\/tr>\n
\n
1951<\/span><\/div>\n<\/td>\n
\n
Acta Psychiatr Neurol Scand. 1951;26(3-4):415-37. <\/span><\/div>\n<\/td>\n
\n
Sex steroid therapy in psychiatric disorders; the therapeutic effect of testosterone and estradiol on hospitalized psychotics: clinical findings.<\/span><\/div>\n<\/td>\n
\n
SACKLER MD, SACKLER RR, SACKLER AM, CO TUI FW, VAN OPHUIJSEN JH.<\/span><\/div>\n<\/td>\n<\/tr>\n
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1952<\/span><\/div>\n<\/td>\n
\n
Br Med J. 1952 Jul 12;2(4775):66-8<\/span><\/div>\n<\/td>\n
\n
Treatment of inadequate personality in juveniles by dehydroisoandrosterone; preliminary report<\/span><\/div>\n<\/td>\n
\n
SANDS DE, CHAMBERLAIN GH<\/span><\/div>\n<\/td>\n<\/tr>\n
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1952<\/span><\/div>\n<\/td>\n
\n
J Clin Endocrinol Metab. 1952 Jul;12(7):831-40.<\/span><\/div>\n<\/td>\n
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Neutral steroid excretion by normal and by schizophrenic men<\/span><\/div>\n<\/td>\n
\n
MITTELMAN A, ROMANOFF LP, PINCUS G, HOAGLAND H<\/span><\/div>\n<\/td>\n<\/tr>\n
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1952<\/span><\/div>\n<\/td>\n
\n\n
Clinical report on the use of testosterone in psychiatric syndromes.<\/span><\/div>\n<\/td>\n
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MARGETTS EL<\/span><\/div>\n<\/td>\n<\/tr>\n
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1953<\/span><\/div>\n<\/td>\n
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Minerva Med. 1953 Aug 11;44(63-64):344-50.<\/span><\/div>\n<\/td>\n
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Use of dehydroisoandrosterone in psychiatry <\/span><\/div>\n<\/td>\n
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ZUBIANI A, LARICCHIA R<\/span><\/div>\n<\/td>\n<\/tr>\n
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1953<\/span><\/div>\n<\/td>\n
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Minerva Med. 1953 Jun 27;44(51):1731-4<\/span><\/div>\n<\/td>\n
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First clinical results of application of dehydroisoandrosterone in the neuropsychiatric field <\/span><\/div>\n<\/td>\n
\n
\n
1953<\/span><\/div>\n<\/td>\n
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Minerva Med. 1953 Jul 28;44(59-60):263-6. <\/span><\/div>\n<\/td>\n
\n
[Preliminary findings on the use of dehydroisoandrosterone in psychiatric <\/span><\/div>\n<\/td>\n
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FERRARI V, DECLICH M.<\/span><\/div>\n<\/td>\n<\/tr>\n
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1953<\/span><\/div>\n<\/td>\n
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Prensa Med Mex. 1953 Apr;18(4):90-8. <\/span><\/div>\n<\/td>\n
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[Treatment of mental deficiency with testosterone.]<\/span><\/div>\n<\/td>\n
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ROCH E, PEINADO ALTABLE J.<\/span><\/div>\n<\/td>\n<\/tr>\n
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1955<\/span><\/div>\n<\/td>\n
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J Neurol Neurosurg Psychiatry. 1955 May;18(2):137-44<\/span><\/div>\n<\/td>\n
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Use of dehydroisoandrosterone in psychiatric practice<\/span><\/div>\n<\/td>\n
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STRAUSS EB, STEVENSON WA.<\/span><\/div>\n<\/td>\n<\/tr>\n
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1955<\/span><\/div>\n<\/td>\n
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Riv Med Aeronaut. 1955 Jan-Mar;18(1):78-88.<\/span><\/div>\n<\/td>\n
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Use of dehydroisoandrosterone in pilots affected with flying fatigue <\/span><\/div>\n<\/td>\n
\n
\n
1955<\/span><\/div>\n<\/td>\n
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J Lancet. 1955 Mar;75(3):109-10.<\/span><\/div>\n<\/td>\n
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Psychiatric use of dehydro-isondrosterone in college students; a pilot study<\/span><\/div>\n<\/td>\n
\n
\n
1955<\/span><\/div>\n<\/td>\n
\n
J Indian Med Assoc. 1955 May 16;24(16):629-30. <\/span><\/div>\n<\/td>\n
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Testosterone in mental disorders.<\/span><\/div>\n<\/td>\n
\n
SINGH K.<\/span><\/div>\n<\/td>\n<\/tr>\n
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1956<\/span><\/div>\n<\/td>\n
\n
Minerva Med. 1956 Jun 23;47(50):1979-85<\/span><\/div>\n<\/td>\n
\n
Dehydroisoandrosterone in mental diseases <\/span><\/div>\n<\/td>\n
\n
\n
1957<\/span><\/div>\n<\/td>\n
\n
Z Gesamte Inn Med. 1957 Oct 15;12(20):922-7<\/span><\/div>\n<\/td>\n
\n
[Use of sexual hormones, especially androgens, in psychic disorders.]<\/span><\/div>\n<\/td>\n
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WENZEL E<\/span><\/div>\n<\/td>\n<\/tr>\n
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1957<\/span><\/div>\n<\/td>\n
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Minerva Med. 1957 Dec 5;48(97):4097-100<\/span><\/div>\n<\/td>\n
\n
[Use of androstenediol in neuropsychiatric therapeutic practice.]<\/span><\/div>\n<\/td>\n
\n
DAZZI P.<\/span><\/div>\n<\/td>\n<\/tr>\n
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1958<\/span><\/div>\n<\/td>\n
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Lyon Med. 1958 May 25;90(21):799-803<\/span><\/div>\n<\/td>\n
\n
[Use of androstanolone base in depressive states & states of a mental weakness;therapeutic note.]<\/span><\/div>\n<\/td>\n
\n
BROUSSOLLE P, LAUXEROIS G.<\/span><\/div>\n<\/td>\n<\/tr>\n
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1961<\/span><\/div>\n<\/td>\n
\n
Dia Med. 1961 Jun 5;33:984-6<\/span><\/div>\n<\/td>\n
\n
Association of long-acting procaine and dehydroisoandrosterone in the geriatric psychophysical revitalizing treatment. Preliminary report <\/span><\/div>\n<\/td>\n
\n
\n
1961<\/span><\/div>\n<\/td>\n
\n
Boll Soc Med Chir Cremona. 1961 Oct-Dec;15:135-46.<\/span><\/div>\n<\/td>\n
\n
[Data on the therapeutic association of nialamide and dehydroisoandrosterone in mental disorders of the female climacteric.]<\/span><\/div>\n<\/td>\n
\n
ZANIBELLI G.<\/span><\/div>\n<\/td>\n<\/tr>\n
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1962<\/span><\/div>\n<\/td>\n
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Dis Nerv Syst. 1962 Apr;23:226-30<\/span><\/div>\n<\/td>\n
\n
Anabolic steroids in the treatment of psychiatric states (effect of oxymetholone<\/span><\/div>\n<\/td>\n
\n
LAPINSOHN LI.<\/a><\/span><\/div>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
 <\/div>\n
 <\/div>\n
Do ponto de vista da simples din\u00e2mica da produ\u00e7\u00e3o cient\u00edfica, esta tend\u00eancia \u00e9 curiosa. Um surto de interesse e investimento numa linha de investiga\u00e7\u00e3o abortado sem o relato de evid\u00eancias negativas. <\/div>\n
Considerando que, se eficaz, o emprego de ester\u00f3ides androg\u00eanicos em desordens mentais teria um custo muito mais baixo do que o das in\u00fameras gera\u00e7\u00f5es de anti-depressivos e neurol\u00e9pticos, esse abortamento d\u00e1 o que pensar. Considerando, um pouco mais, que o emprego de ester\u00f3ides androg\u00eanicos n\u00e3o inibe a iniciativa dos pacientes, nem tampouco sua libido e muito menos sua capacidade cognitiva \u2013 todas essas fun\u00e7\u00f5es fortemente prejudicadas pelas drogas psicotr\u00f3picas atualmente em uso \u2013 esse abortamento d\u00e1 ainda mais o que pensar.<\/div>\n","protected":false},"excerpt":{"rendered":"

Fiz um levantamento na literatura m\u00e9dica por pesquisas relativas ao efeito e emprego de ester\u00f3ides androg\u00eanicos anab\u00f3licos em sa\u00fade mental. Quanto \u00e0s d\u00e9cadas recentes, observei o \u00f3bvio: nenhuma pesquisa. Tudo que h\u00e1 em rela\u00e7\u00e3o ao tema s\u00e3o relatos de uma suposta depend\u00eancia de ester\u00f3ides e seus desdobramentos negativos. No entanto, expandindo a busca para datas […]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_seopress_robots_primary_cat":"","_seopress_titles_title":"","_seopress_titles_desc":"","_seopress_robots_index":"","site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[19],"tags":[],"_links":{"self":[{"href":"https:\/\/www.mariliacoutinho.com\/pt-br\/wp-json\/wp\/v2\/posts\/5293"}],"collection":[{"href":"https:\/\/www.mariliacoutinho.com\/pt-br\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.mariliacoutinho.com\/pt-br\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.mariliacoutinho.com\/pt-br\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.mariliacoutinho.com\/pt-br\/wp-json\/wp\/v2\/comments?post=5293"}],"version-history":[{"count":0,"href":"https:\/\/www.mariliacoutinho.com\/pt-br\/wp-json\/wp\/v2\/posts\/5293\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.mariliacoutinho.com\/pt-br\/wp-json\/wp\/v2\/media?parent=5293"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.mariliacoutinho.com\/pt-br\/wp-json\/wp\/v2\/categories?post=5293"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.mariliacoutinho.com\/pt-br\/wp-json\/wp\/v2\/tags?post=5293"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}